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GSK2830371
Artikelnummer: Cay16973-5
The wild-type p53-induced phosphatase Wip1, also known as protein phosphatase magnesium-dependent 1 delta (PPM1D) or PP2Cdelta, modulates cell cycling and may contribute to some forms of cancer. GSK2830371 is a potent inhibitor of Wip1 (IC50 = 6 nM). It displays selectivity for Wip1 over 21 other phosphatases....
| Schlagworte: | 5-[[(5-chloro-2-methyl-3-pyridinyl)amino]methyl]-N-[(1S)-1-(cyclopentylmethyl)-2-(cyclopropylamino)-2-oxoethyl]-2-thiophen... |
| Anwendung: | PPM1D / WIP1 inhibitor |
| CAS | 1404456-53-6 |
| MW: | 461 D |
ab 49,00 €
GSK-2830371
Artikelnummer: LKT-G7240.1
Wip1 inhibitor.
| Anwendung: | Wip1 inhibitor |
| CAS | 1404456-53-6 |
| MW: | 461.02 D |
ab 94,00 €
GSK 2830371
Artikelnummer: TGM-T6521-100mg
Description: GSK 2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM. Target: Phosphatase. Smiles: Cc1ncc(Cl)cc1NCc1ccc(s1)C(=O)N[C@@H](CC1CCCC1)C(=O)NC1CC1. References: Gilmartin AG, et al. Nat Chem Biol. 2014, 10(3), 181-187
| Schlagworte: | GSK2830371 |
| Anwendung: | PPM1D / WIP1 inhibitor |
| CAS | 1404456-53-6 |
| MW: | 461.02 D |
ab 46,00 €
