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G-36
Artikelnummer: Cay14397-1
G protein-coupled estrogen receptor (GPER), or GPR30, specifically binds natural and man-made estrogens. It is thought to be involved in estrogen-sensitive cancers. GPER knockout mice are fertile, although they exhibit thymic atrophy, impaired glucose tolerance, and altered bone growth. G-36 is a cell-permeable...
| Schlagworte: | (4S)-rel-4-(6-bromo-1,3-benzodioxol-5-yl)-3aR,4,5,9bS-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline |
| Anwendung: | GPER antagonist |
| CAS | 1392487-51-2 |
| MW: | 412.3 D |
ab 49,00 €
G36
Artikelnummer: TGM-T22794-10mg
Description: G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17beta-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively). G36 has no detectable binding activity to either ERalpha or ERbeta. G36 blocks the activation of PI3K or calcium...
| Schlagworte: | G-36 |
| CAS | 1392487-51-2 |
| MW: | 412.32 D |
ab 33,00 €
