Zu "138516-31-1" wurden 3 Artikel gefunden!
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Bisindolylmaleimide VIII (acetate)
Artikelnummer: Cay13333-1
Bisindolylmaleimide VIII (BIM VIII) is a selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. This compound exhibits some degree of PKC isozyme specificity with preference for PKCalpha over PKCbetaI, PKCbetaII, PKCgamma, or PKCepsilon (IC50s = 53,...
| Schlagworte: | BIM VIII, Ro 31-7549, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, acetate |
| Anwendung: | PKC inhibitor |
| CAS | 138516-31-1 |
| MW: | 458.5 D |
ab 75,00 €
Bisindolylmaleimide VIII-AcOH
Artikelnummer: AG-CR1-0114-M001
Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2).
| Schlagworte: | Ro 31-7549, BIM VIII |
| Anwendung: | PKC inhibitor |
| CAS | 138516-31-1 |
ab 61,00 €
Bisindolylmaleimide VIII acetate
Artikelnummer: TGM-T10549-100mg
Description: Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC) with IC50 values of 53, 195, 163, 213, and 175 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively. Target: PKC, Apoptosis. Smiles:...
| Schlagworte: | Bis VIII acetate, Ro 31-7549 acetate |
| CAS | 138516-31-1 |
| MW: | 458.51 D |
ab 38,00 €
