Zu "138489-18-6" wurden 2 Artikel gefunden!
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Bisindolylmaleimide IX (mesylate)
Artikelnummer: Cay13334-1
Bisindolylmaleimide IX (BIM IX) is a potent, cell-permeable inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It is a poor inhibitor of protein kinase A (PKA, IC50 = 0.9 µM) and calcium/calmodulin kinase II...
| Schlagworte: | BIM IX, Ro 31-8220, carbamimidothioic acid,... |
| Anwendung: | PKC inhibitor |
| CAS | 138489-18-6 |
| MW: | 553.7 D |
ab 60,00 €
Bisindolylmaleimide IX-Methansulfonate
Artikelnummer: AG-CR1-0111-M001
Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces TNF receptor family-mediated cell death. Pim-1 kinase...
| Schlagworte: | Ro 31-8220, BIM IX |
| Anwendung: | PKC inhibitor |
| CAS | 138489-18-6 |
ab 66,00 €
