Zu "1380432-32-5" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
EHop-016
Artikelnummer: Cay21557-5
EHop-016 is an inhibitor of the small Rho GTPases Rac1 and Rac3. It inhibits Rac1 activity in MDA-MB-435 breast cancer cells with an IC50 value of 1.1 µM in a Rac1 activation assay. At a concentration of 1 µM, EHop-016 inhibits 58% of Rac3 activity, and it inhibits Cdc42 activity but only at higher concentrations...
| Schlagworte: | N4-(9-ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine |
| Anwendung: | RAC1 / RAC3 inhibitor |
| CAS | 1380432-32-5 |
| MW: | 430.6 D |
ab 76,00 €
EHop-016
Artikelnummer: TGM-T2427-100mg
Description: EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 µM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3. Target: Ras, Rho. Smiles: CCn1c2ccccc2c2cc(Nc3ccnc(NCCCN4CCOCC4)n3)ccc12. References: Montalvo-Ortiz BL, et al. J Biol Chem. 2012, 287(16), 13228-13238.
| Schlagworte: | EHop 016 |
| CAS | 1380432-32-5 |
| MW: | 430.55 D |
ab 39,00 €
