Zu "1375466-18-4" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
ACY-775
Artikelnummer: AG-CR1-3903-M001
Off white solid. Soluble in DMSO, methanol or ethanol. Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =7.5nM). Displays high selectivity over HDAC1-9 (IC50=1-10µ,M), Shows improved brain bioavailability compared to tubastatin A (Prod. No. AG-CR1-3900), Induces hyperacetylation of...
| Schlagworte: | 2-((1-(3-Fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide |
| Anwendung: | HDAC6 inhibitor |
| CAS | 1375466-18-4 |
| MW: | 330,4 D |
ab 50,00 €
ACY-775
Artikelnummer: Cay29198-1
ACY-775 is an inhibitor of histone deacetylase 6 (HDAC6, IC50 = 0.0075 µM). It is selective for HDAC6 over HDAC1, HDAC2, and HDAC3 (IC50s = 2.1, 2.5, and 11.2 µM, respectively). ACY-775 (2.5 µM) increases alpha-tubulin acetylation at lysine 40 in RN46A-B14 serotonergic cells. It increases the distance traveled in...
| Schlagworte: | 2-[[1-(3-fluorophenyl)cyclohexyl]amino]-N-hydroxy-5-pyrimidinecarboxamide |
| Anwendung: | HDAC6 inhibitor |
| CAS | 1375466-18-4 |
| MW: | 330.4 D |
ab 49,00 €
ACY-775
Artikelnummer: TGM-TQ0074-100mg
Description: ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM). Target: HDAC. Smiles: ONC(=O)c1cnc(NC2(CCCCC2)c2cccc(F)c2)nc1. References: Jeanine Jochems et al. Antidepressant-Like Properties of Novel HDAC6-Selective Inhibitors with Improved Brain Bioavailability. Neuropsychopharmacology. 2014...
| Anwendung: | HDAC6 inhibitor |
| CAS | 1375466-18-4 |
| MW: | 330.36 D |
ab 41,00 €
