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C25-140
Artikelnummer: TGM-T7889-100mg
Description: C25-140 is a small-molecule inhibitor of TRAF6-Ubc13. Target: TNF, E1/E2/E3 Enzyme, Others, NF-kappaB. Smiles: Cc1nn(c(C)c1CCC(=O)N1CCC(Cc2ccccc2)CC1)-c1ccc2nnc(C)n2n1. References: Kerstin B J , Maria P G , Kenji S , et al. Targeting TRAF6 E3 ligase activity with a small molecule inhibitor combats...
| Anwendung: | TRAF6-Ubc13 protein-protein interaction inhibitor |
| CAS | 1358099-18-9 |
| MW: | 457.57 D |
ab 67,00 €
C25-140
Artikelnummer: Cay39669-1
C25-140 is an inhibitor of the protein-protein interaction between the E3 ligase TNF receptor-associated factor 6 (TRAF6) and ubiquitin-conjugating enzyme E2 N (Ubc13, IC50 = 2.6 µM). It selectively inhibits the TRAF6-Ubc13 interaction over the interactions between Ubc13-OTUB1 and Ubc13-Uev1a. C25-140 (30 µM) also...
| Schlagworte: | 3-[3,5-dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-1-pro... |
| Anwendung: | TRAF6-Ubc13 protein-protein interaction inhibitor |
| CAS | 1358099-18-9 |
| MW: | 457.6 D |
ab 54,00 €
