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Belizatinib
Artikelnummer: Cay28458-1
Belizatinib is an inhibitor of anaplastic lymphoma kinase (ALK) and tropomyosin-related kinases A/B/C (IC50s = 0.7 and 98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 324 nm. SMILES:...
| Schlagworte: | TSR-011,... |
| Anwendung: | ALK inhibitor, TrkA/TrkB/TrkC inhibitor |
| CAS | 1357920-84-3 |
| MW: | 577.7 D |
ab 56,00 €
Belizatinib
Artikelnummer: TGM-T4257-100mg
Description: Belizatinib (TSR-011) is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC. Target: Trk receptor, ALK. Smiles: CC(C)NC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2ccc(F)cc2)nc2ccc(CN3CCC(CC3)C(C)(C)O)cc12. References: Sullivan I, et al. ALK inhibitors...
| Schlagworte: | TSR-011 |
| Anwendung: | ALK inhibitor, TrkA/TrkB/TrkC inhibitor |
| CAS | 1357920-84-3 |
| MW: | 577.73 D |
ab 35,00 €
