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CYM 50260
Artikelnummer: Cay14560-1
CYM 50260 is an agonist of sphingosine-1-phosphate receptor 4 (S1P4). It induces gene transcription in a reporter assay using U2OS cells expressing human S1P4 (EC50 = 45 nM). CYM 50260 (25 µM) inhibits collagen-induced increases in PDGF-AB secretion from, and phosphorylated heat shock protein 27 (Hsp27) levels in,...
| Schlagworte: | 2-chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)-pyridine |
| Anwendung: | Sphingosine 1-phosphate receptor 4 (S1PR4, EDG6) agonist |
| CAS | 1355026-60-6 |
| MW: | 350.6 D |
ab 45,00 €
CYM50260
Artikelnummer: TGM-T15031-100mg
Description: CYM50260 is a potent and highly selective agonist of the sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM), exhibiting no activity against S1P1-R, S1P2-R, S1P3-R, and S1P5-R. Target: LPL Receptor, Others. Smiles: FCc1ccc(OCCOc2ccc(Cl)cc2Cl)c(Cl)n1. References: Guerrero M, et al. Discovery, design...
| CAS | 1355026-60-6 |
| MW: | 350.6 D |
ab 46,00 €
