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Elacestrant dihydrochloride
Artikelnummer: TGM-T13675-100mg
Description: Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERalpha and 870 nM for ERbeta, respectively. Target: Estrogen/progestogen Receptor. Smiles: Cl.Cl.CCNCCc1ccc(CN(CC)c2cc(OC)ccc2[C@@H]2CCc3cc(O)ccc3C2)cc1....
| Schlagworte: | RAD1901 dihydrochloride |
| Anwendung: | Targets estrogen receptor alpha (ESR1, NR3A1) |
| CAS | 1349723-93-8 |
| MW: | 531.56 D |
ab 120,00 €
Elacestrant (hydrochloride)
Artikelnummer: Cay37298-1
Elacestrant is a selective estrogen receptor degrader (SERD). It selectively binds to estrogen receptor alpha (ERalpha) over ERbeta (IC50s = 48 and 870 nM, respectively) and reduces ERalpha levels in MCF-7 cells (EC50 = 0.6 nM). Elacestrant reduces MCF-7 proliferation induced by 17beta-estradiol (E2, Cay-10006315)...
| Schlagworte: | RAD901, 6R-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol,... |
| Anwendung: | Selective estrogen receptor degrader, SERD |
| CAS | 1349723-93-8 |
| MW: | 531.6 D |
ab 49,00 €
