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Avacopan
Artikelnummer: TGM-T8223-1mg
Description: Avacopan (CCX168) is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model of AAV. Target: Complement System. Smiles:...
| Schlagworte: | CCX168 |
| Anwendung: | Targets C5a anaphylatoxin chemotactic receptor 1 (C5AR1, CD88) |
| CAS | 1346623-17-3 |
| MW: | 581.64 D |
ab 34,00 €
Avacopan
Artikelnummer: Cay36639-1
Avacopan is an antagonist of the complement 5a1 (C5a1) receptor (IC50 = 0.1 nM). It is selective for C5a1 over the C5a2 receptor and chemokine-like receptor 2 (CMKLR2), also known as chemerin receptor 2 or GPR1 (IC50s = >10,000 nM for both), as well as the C3a receptor, CMKLR1, and formyl peptide receptor 1 (FPR1,...
| Schlagworte: | CCX168,... |
| Anwendung: | Antiinflammatory, complement C5a1 receptor antagonist |
| CAS | 1346623-17-3 |
| MW: | 581.6 D |
ab 44,00 €
