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LY2795050
Artikelnummer: Cay33604-1
LY2795050 is a kappa-opioid receptor antagonist (Ki = 0.722 nM). It is selective for kappa-opioid receptors over µ- and delta-opioid receptors (Kis = 25.8 and 153 nM, respectively). LY2795050 (0.1 mg/kg, i.p.) reduces immobility time in the forced swim test, as well as reduces salvinorin A-induced decreases in...
| Schlagworte: | 3-chloro-4-[4-[[(2S)-2-(3-pyridinyl)-1-pyrrolidinyl]methyl]phenoxy]-benzamide |
| Anwendung: | Kappa-opioid receptor antagonist |
| CAS | 1346133-08-1 |
| MW: | 407.9 D |
ab 110,00 €
LY2795050
Artikelnummer: TGM-TQ0091-10mg
Description: LY2795050 is a novel specific kappa-Opioid Receptor antagonist (IC50: 0.72 nM). Target: Opioid Receptor. Smiles: NC(=O)c1ccc(Oc2ccc(CN3CCC[C@H]3c3cccnc3)cc2)c(Cl)c1. References: Mitch, Charles H., Quimby, Steven J., Diaz, Nuria, et al. Discovery of Aminobenzyloxyarylamides as kappa Opioid Receptor...
| Anwendung: | Kappa-opioid receptor antagonist |
| CAS | 1346133-08-1 |
| MW: | 407.89 D |
ab 46,00 €
