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XMD16-5
Artikelnummer: TGM-T3710-100mg
Description: XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted metastasis in a mouse model of breast Y. TNK2 signaling is disrupted in breast, prostate and gastrointestinal tumors. Target: PPAR, Tyrosinase....
| Anwendung: | TNK2 inhibitor |
| CAS | 1345098-78-3 |
| MW: | 416.48 D |
ab 38,00 €
XMD16-5
Artikelnummer: Cay23353-1
XMD16-5 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2, IC50 = 0.38 µM), which contains mutations in certain cancer cells. It also decreases viability of Ba/F3 cells expressing the oncogenic TNK2 D163E and R806Q mutant proteins (IC50s = 16 and 77 nM, respectively) without affecting viability of parental...
| Schlagworte: | 5,11-dihydro-2-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Anwendung: | TNK2 inhibitor |
| CAS | 1345098-78-3 |
| MW: | 416.5 D |
ab 52,00 €
