Zu "1335106-03-0" wurden 3 Artikel gefunden!
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SR 1001
Artikelnummer: Cay10922-1
Retinoic-acid-receptor-related orphan receptors (ROR) alpha and gamma play a key role in the development of T-helper cells that produce interleukin-17 (TH17 cells), a subset of CD4+ T-cells that contribute to the inflammatory process and have been implicated in the pathology of autoimmune diseases. SR 1001 is a...
| Schlagworte: | N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulfamoyl)-4-methylthiazol-2-yl)acetamide |
| Anwendung: | RORalpha and RORgamma inverse agonist |
| CAS | 1335106-03-0 |
| MW: | 477.4 D |
ab 49,00 €
SR1001
Artikelnummer: LKT-S6800.5
RORalpha/gamma inverse agonist.
| Anwendung: | RORalpha/gamma inverse agonist |
| CAS | 1335106-03-0 |
| MW: | 477.4 D |
ab 86,00 €
SR1001
Artikelnummer: TGM-T5163-100mg
Description: SR 1001 is an inverse agonist for RORalpha/RORgamma (Kis: 172/111 nM). Target: ROR. Smiles: CC(=O)Nc1nc(C)c(s1)S(=O)(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F. References: Solt LA, et al. Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature. 2011 Apr 28,472(7344):491-4.
| Anwendung: | RORalpha and RORgamma inverse agonist |
| CAS | 1335106-03-0 |
| MW: | 477.4 D |
ab 33,00 €
