Zu "1333377-65-3" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
CHR-6494
Artikelnummer: TGM-T14959-5mg
Description: CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM). Target: Others. Smiles: OC(=O)C(F)(F)F.CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1. References: Huertas D, et al. Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene. 2012 Mar...
| Anwendung: | Haspin Kinase Inhibitor |
| CAS | 1333377-65-3 |
| MW: | 292.34 D |
ab 49,00 €
CHR-6494
Artikelnummer: Cay11478-1
CHR-6494 is a haspin protein kinase inhibitor (IC50 = 2 nM) selective over 27 other protein kinases, including Aurora B kinase (IC50 > 1 µM). Haspin is a kinase necessary for mitosis that selectively phosphorylates histone 3 at the threonine 3 residue (H3T3ph). CHR-6494 decreases phosphorylation of H3T3 and arrests...
| Schlagworte: | 3-(1H-indazol-5-yl)-N-propyl-imidazo[1,2-b]pyridazin-6-amine |
| Anwendung: | Haspin Kinase Inhibitor |
| CAS | 1333377-65-3 |
| MW: | 292.3 D |
ab 49,00 €
