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Bisindolylmaleimide I
Artikelnummer: Cay13298-5
Bisindolylmaleimide I (BIM I) is a highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM) that is structurally similar to the poorly selective PKC inhibitor staurosporine (Cay-81590). It acts as a competitive inhibitor for the ATP binding site of PKC and shows high selectivity for PKCalpha,...
| Schlagworte: | BIM I, GF 109203X, Gö 6850, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Anwendung: | PKC inhibitor |
| CAS | 133052-90-1 |
| MW: | 412.5 D |
ab 128,00 €
Bisindolylmaleimide I
Artikelnummer: AG-CR1-0009-M001
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM), Competetive inhibitor for the ATP-binding site of PKC, Anti-inflammatory, Binds to P-glycoprotein, Telomerase activity inhibitor, Potent glycogen synthase kinase-3 (GSK-3) inhibitor, Inhibits necrosis, Blocks hERG...
| Schlagworte: | GF-109203X, Gö 6850 |
| Anwendung: | PKC inhibitor |
| CAS | 133052-90-1 |
| MW: | 412,5 D |
ab 66,00 €
Bisindolylmaleimide I
Artikelnummer: TGM-T6513-100mg
Description: Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor, exhibiting a Ki of 14 nM. Target: PDGFR, PKC. Smiles: CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12. References: Toullec D, et al. J Biol Chem. 1991, 266(24), 15771-15781.
| Schlagworte: | Go 6850, GF109203X |
| Anwendung: | PKC inhibitor |
| CAS | 133052-90-1 |
| MW: | 412.48 D |
ab 57,00 €
