Zu "1316755-16-4" wurden 2 Artikel gefunden!
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EMA401
Artikelnummer: Cay22988-1
EMA401 is an orally bioavailable and selective antagonist of the angiotensin II type 2 receptor (AT2, IC50s = 39.5 and 408,000 nM for rat recombinant AT2 and AT1, respectively). It inhibits capsaicin-induced calcium influx in cultured human dorsal root ganglion (hDRG) neurons (IC50 = 10 nM) and reduces neurite...
| Schlagworte: | (3S)-2-(2,2-diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic acid |
| Anwendung: | Angiotensin II type 2 receptor antagonist |
| CAS | 1316755-16-4 |
| MW: | 507.6 D |
ab 84,00 €
Olodanrigan
Artikelnummer: TGM-T4431-100mg
Description: Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. EMA401 blocks p38, p42/p44 mitogen-activated protein kinase (MAPK) activation, neurite...
| Schlagworte: | PD-126055 , EMA401 |
| Anwendung: | Angiotensin II type 2 receptor antagonist |
| CAS | 1316755-16-4 |
| MW: | 507.58 D |
ab 34,00 €
