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AMZ30
Artikelnummer: TGM-T5182-100mg
Description: AMZ30 is a selective inhibitor of PME-1 (IC50: 600 nM). It also reduces the demethylated form of PP2A in living cells. Target: Others. Smiles: [O-][N+](=O)c1cccc(c1)S(=O)(=O)n1cccc1\C=C(/C#N)S(=O)(=O)c1ccc(F)cc1. References: Bachovchin DA, et al. Discovery and optimization of sulfonyl acrylonitriles as...
| CAS | 1313613-09-0 |
| MW: | 461.44 D |
ab 31,00 €
AMZ30
Artikelnummer: Cay42052-10
A covalent inhibitor of PME-1 (IC50 = 0.6 µM), reduces the levels of methylated PP2A in HEK293T cells stably overexpressing PME-1 at 20 µM. AMZ30, inhibits t-BHP-induced decreases in U87MG and U-251MG cells at 210 µM. Formulation: A crystalline solid. InChI:...
| Schlagworte: | ML-136, (2E)-2-[(4-fluorophenyl)sulfonyl]-3-[1-[(3-nitrophenyl)sulfonyl]-1H-pyrrol-2-yl]-2-propenenitrile |
| Anwendung: | Protein phosphatase methylesterase 1 (PME-1, PPME1) covalent inhibitor |
| CAS | 1313613-09-0 |
| MW: | 461.45 D |
ab 120,00 €
