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NB-598
Artikelnummer: TGM-TQ0115-100mg
Description: NB-598 is an effective and competitive inhibitor of squalene epoxidase. It suppresses triglyceride biosynthesis through the farnesol pathway. Target: Antifungal. Smiles: CCN(C\C=C\C#CC(C)(C)C)Cc1cccc(OCc2cc(cs2)-c2ccsc2)c1. References: Horie M, et al. Effects of NB-598, a potent squalene epoxidase...
| Anwendung: | Squalene epoxidase inhibitor |
| CAS | 131060-14-5 |
| MW: | 449.67 D |
ab 72,00 €
NB-598
Artikelnummer: Cay14912-5
NB-598 is an inhibitor of squalene epoxidase (IC50s = 2 and 0.75 nM for dog liver and human microsomal enzymes, respectively). It selectively inhibits cholesterol synthesis over free fatty acid, triglyceride, and phospholipid synthesis in HepG2 cells at 1 µM. NB-598 (10 mg/kg per day) reduces serum cholesterol...
| Schlagworte: | 3-([3,3'-bithiophen]-5-ylmethoxy)-N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-ethyl-benzenemethanamine |
| Anwendung: | Squalene epoxidase inhibitor |
| CAS | 131060-14-5 |
| MW: | 449.7 D |
ab 36,00 €
