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Sephin1
Artikelnummer: Cay17757-1
Protein phosphatase 1C (PP1c) dephosphorylates the eukaryotic translation initiation factor 2alpha subunit (eIF2alpha) to turn off the unfolded protein response in the endoplasmic reticulum (ER). PP1c removes phosphates on eIF2alpha under the direction of one of two accessory subunits termed protein phosphatase 1...
| Schlagworte: | NSC 65390, 2-[(2-chlorophenyl)methylene]-hydrazinecarboximidamide |
| Anwendung: | Selective PPP1R15A inhibitor |
| CAS | 13098-73-2 |
| MW: | 196.6 D |
ab 89,00 €
Sephin1
Artikelnummer: TGM-T21824-100mg
Description: Sephin1 (IFB-088) is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2alpha. Target: Phosphatase. Smiles: C(=NNC(=N)N)C1=C(Cl)C=CC=C1. References: Ruiz A , Zuazo J , Ortiz-Sanz C , et al....
| Schlagworte: | NSC 65390, IFB-088 |
| CAS | 13098-73-2 |
| MW: | 196.64 D |
ab 29,00 €
