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I-BET151
Artikelnummer: TGM-T2120-100mg
Description: I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 µM, in cell-free assays). Target: Epigenetic Reader Domain. Smiles: Cl.COc1cc2c3n([C@H](C)c4ccccn4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C. References: Dawson MA, et al. Nature, 2011, 478(7370), 529-533.
| Schlagworte: | GSK1210151A |
| CAS | 1300031-49-5 |
| MW: | 415.44 D |
ab 42,00 €
I-BET151
Artikelnummer: Cay11181-5
The bromodomain and extra terminal domain (BET) family of proteins including BRD2, BRD3, and BRD4 play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. I-BET151 is an...
| Schlagworte: | GSK1210151A, 7,3,5-dimethyl-4-isoxazolyl-1,3-dihydro-8-methoxy-1-[1R-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one |
| Anwendung: | pan-BET family inhibitor |
| CAS | 1300031-49-5 |
| MW: | 415.5 D |
ab 49,00 €
I-BET151
Artikelnummer: LKT-I0516.25
I-BET-151 is a BET bromodomain (BRD) inhibitor that inhibits BRD2, BRD3, and BRD4. I-BET-151 exhibits anticancer chemotherapeutic and anti-inflammatory activities. In vitro and in vivo, this compound induces apoptosis and inhibits cellular proliferation in various cancer models. I-BET-151 inhibits recruitment of the...
| Schlagworte: | GSK-1210151A, GSK1210151A |
| Anwendung: | pan-BET family inhibitor |
| CAS | 1300031-49-5 |
| MW: | 415.44 D |
ab 248,00 €
