Zu "129425-81-6" wurden 4 Artikel gefunden!
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MSA-2
Artikelnummer: LKT-M721002.100
MSA-2 is an agonist of stimulator of interferon genes (STING). SMILES: COC1=C(C=C2C(=C1)C=C(S2)C(=O)CCC(=O)O)OC
| Schlagworte: | MSA2, 4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid |
| Anwendung: | STING agonist |
| CAS | 129425-81-6 |
| MW: | 294.32 D |
ab 145,00 €
MSA-2
Artikelnummer: TGM-T8798-100mg
Description: MSA-2 is a potent and orally available non-nucleotide STING agonist. Target: STING. Smiles: COc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O. References: Pan BS, et al. An orally available non-nucleotide STING agonist with antitumor activity. Science. 2020,369(6506):eaba6098.
| Anwendung: | STING agonist |
| CAS | 129425-81-6 |
| MW: | 294.32 D |
ab 34,00 €
MSA-2
Artikelnummer: Cay30140-10
MSA-2 is an agonist of stimulator of interferon genes (STING). It binds to wild-type and HAQ variant STING in a 3H-cGAMP filtration binding assay (EC50s = 2.48 and 1.72 µM, respectively) and induces secretion of IFN-beta from THP-1 cells by 129% relative to induction by 2'3'-cGAMP (Cay-19887) when used at a...
| Schlagworte: | 5,6-dimethoxy-gamma-oxo-benzo[b]thiophene-2-Butanoic Acid |
| Anwendung: | STING agonist |
| CAS | 129425-81-6 |
| MW: | 294.3 D |
ab 44,00 €
MSA-2
Artikelnummer: AG-CR1-0164-M001
MSA-2 is a new orally available non-nucleotide STING (STimulator of INterferon Genes) agonist, with EC50s of 8.3 and 24µM for human STING isoforms WT and HAQ. Activation of the STING protein by its natural ligand, cyclic guanosine monophosphate-adenosine monophosphate (cGAMP, a cytosolic double-stranded DNA sensor),...
| CAS | 129425-81-6 |
ab 44,00 €
