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DPQ
Artikelnummer: Cay14450-1
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can...
| Schlagworte: | PARP Inhibitor III, 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone |
| Anwendung: | PARP inhibitor |
| CAS | 129075-73-6 |
| MW: | 302.4 D |
ab 84,00 €
DPQ
Artikelnummer: AG-CR1-0037-M001
Very potent PARP-1 inhibitor.
| Schlagworte: | 3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone |
| Anwendung: | PARP-1 inhibitor |
| CAS | 129075-73-6 |
| MW: | 302,4 D |
ab 55,00 €
DPQ
Artikelnummer: TGM-T60695-100mg
Description: DPQ is a potent inhibitor of PARP-1 that can be used in neuroprotection research. DPQ reduce the PARP activation induced by N-methyl-d-aspartate (NMDA), restoring ATP to near control levels as well as significantly attenuating neuronal injury in the severe NMDA exposure model [1]. Target: Others....
| Anwendung: | PARP-1 inhibitor |
| CAS | 129075-73-6 |
| MW: | 302.41 D |
ab 896,00 €
