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PF-04753299
Artikelnummer: Cay36502-1
PF-04753299 is an inhibitor of LpxC (IC50 = 1.37 nM), a bacterial deacetylase involved in the biosynthesis of LPS lipid A. It is selective for LpxC over a panel of 16 human matrix metalloproteinases (MMPs, Kis = >1 µM for all). PF-04753299 is active against P. aeruginosa, K. pneumoniae, E. coli, E. aerogenes, C....
| Schlagworte: | N-hydroxy-alphaR-methyl-alpha-(methylsulfonyl)-[1,1'-biphenyl]-4-butanamide |
| Anwendung: | LpxC inhibitor |
| CAS | 1289620-49-0 |
| MW: | 347.4 D |
ab 53,00 €
PF-04753299
Artikelnummer: TGM-T41275-10mg
Description: PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates and exhibiting inhibitory activity against E. coli, P. aeruginosa, and K. pneumoniae, with minimum inhibitory...
| Anwendung: | LpxC inhibitor |
| CAS | 1289620-49-0 |
| MW: | 347.43 D |
ab 65,00 €
