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YLF-466D
Artikelnummer: Cay19475-1
YLF-466D is an orally bioavailable activator of AMP-activated protein kinase (AMPK), an enzyme involved in regulation of cellular energy homeostasis. YLF-466D activates AMPK at a concentration of 150 µM in platelets. It inhibits platelet aggregation induced by thrombin, ADP, and collagen (IC50s = 84, 55, and 87 µM,...
| Schlagworte: | 3-[[(3E)-3-[(4-chlorophenyl)phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-1-yl]methyl]-benzoic acid |
| Anwendung: | AMPK activator |
| CAS | 1273323-67-3 |
| MW: | 465.9 D |
ab 164,00 €
YLF-466D
Artikelnummer: TGM-T13368-100mg
Description: YLF-466D (C24) is a novel AMPK activator that inhibits platelet aggregation. Target: AMPK. Smiles: OC(=O)c1cccc(CN2C(=O)\C(=C(/c3ccccc3)c3ccc(Cl)cc3)c3ccccc23)c1. References: Liu Y, et al. Antiplatelet effect of a newly developed AMP-activated protein kinase activator YLF-466D. Eur J Pharmacol. 2015 Aug...
| Schlagworte: | C24 |
| Anwendung: | AMPK activator |
| CAS | 1273323-67-3 |
| MW: | 465.93 D |
ab 30,00 €
