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Ciclesonide
Ciclesonide

Artikelnummer: LKT-C324091.100

Ciclesonide is an anti-inflammatory corticosteroid. Its active metabolite and several ciclesonide-acetal derivatives have been found to block RNA replication of the SARS-Cov-2 virus. Ciclesonide also inhibits lung cancer stem cells through Hedgehog signaling-mediated SOX2 regulation. Solubility: Insoluble in water....
Schlagworte: Alvesco, Omnaris, Zetonna, RPR251526, (R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal...
Anwendung: Corticosteroid
CAS 126544-47-6
MW: 540.7 D
ab 138,00 €
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Ciclesonide
Ciclesonide

Artikelnummer: Cay18227-1

Ciclesonide (CIC) is a prodrug form of the glucocorticoid receptor agonist desisobutyryl-CIC (des-CIC). CIC binds to the glucocorticoid receptor with a Ki value of 37 nM. It is selective for the glucocorticoid receptor over the estrogen, progesterone, and testosterone receptors. CIC inhibits eosinophil influx into...
Schlagworte: CIC, RPR 251526,...
Anwendung: Glucocorticoid receptor agonist
CAS 126544-47-6
MW: 540.7 D
ab 44,00 €
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Ciclesonide
Ciclesonide

Artikelnummer: TGM-T2526-100mg

Description: Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases. Target: Glucocorticoid Receptor. Smiles: C(COC(C(C)C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@H](O2)[C@@H]4CCCCC4)[H])([C@]5([C@]([C@@H](O)C3)([C@]6(C)C(CC5)=CC(=O)C=C6)[H])[H])[H]. References: Guo...
Schlagworte: Alvesco, RPR251526, Omnaris, Zetonna
Anwendung: Targets glucocorticoid receptor (NR3C1, GR)
CAS 126544-47-6
MW: 540.69 D
ab 45,00 €
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