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SR-12813
Artikelnummer: Cay18115-10
SR-12813 is a 1,1-bisphosphonate ester that exhibits hypocholesterolemic activity by enhancing the degradation of HMG-CoA reductase in various animal models. SR-12813 is also a high affinity ligand for human and rabbit pregnane X receptors (Kd = 41 nM, EC50 = 137 nM for hPXR in vitro) and can induce cytochrome P450...
| Schlagworte: | GW 485801, P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonic acid P,P,P',P'-tetraethyl ester |
| Anwendung: | HMG-CoA reductase degradation enhancer, Pregnane X receptor ligand |
| CAS | 126411-39-0 |
| MW: | 504.5 D |
ab 115,00 €
