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Cenerimod
Artikelnummer: Cay29665-10
Cenerimod is a sphingosine-1-phosphate receptor 1 (S1P1) modulator with an EC50 value of 1 nM in a [35S]GTP?S binding assay. It is selective for S1P1 over S1P2, -3, -4, and -5 (EC50s = >10,000, 228, 2,137, and 36 nM, respectively). Cenerimod (5 µM) decreases TGF-beta-induced increases in collagen levels in primary...
| Schlagworte: | (2S)-3-[4-[5-(2-cyclopentyl-6-methoxy-4-pyridinyl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-1,2-propanediol |
| Anwendung: | Sphingosine-1-phosphate receptor 1 (S1P1) modulator |
| CAS | 1262414-04-9 |
| MW: | 453.5 D |
ab 108,00 €
Cenerimod
Artikelnummer: TGM-T14924-10mg
Description: Cenerimod (ACT-334441) is an orally active, selective, and potent sphingosine 1-phosphate receptor (S1P1) agonist (EC50: 1 nM).Cenerimod inhibits multiple S1P isoforms and can be used to study murine experimental autoimmune encephalomyelitis (EAE) and murine scleroderma. Target: S1P Receptor. Smiles:...
| Schlagworte: | ACT-334441 |
| Anwendung: | Targets sphingosine 1-phosphate receptor 1 (S1PR1, EDG1, CD363) |
| CAS | 1262414-04-9 |
| MW: | 453.53 D |
ab 34,00 €
