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Birinapant
Artikelnummer: Cay19699-5
Birinapant is a bivalent mimetic of the Diablo homolog known as second mitochondria-derived activator of caspase (Smac). It is an antagonist of cellular inhibitor of apoptosis 1 (cIAP1, or BIRC2), cIAP2 (BIRC3), and XIAP (BIRC4), binding each at nanomolar concentrations. Birinapant causes rapid cIAP1 degradation,...
| Schlagworte: | TL-32711,... |
| Anwendung: | Antineoplastic, XIAP / cIAP1 inhibitor |
| CAS | 1260251-31-7 |
| MW: | 806.9 D |
ab 85,00 €
TL-32711
Artikelnummer: LKT-T4400.10
TL-32711 is a Smac mimetic that is currently in clinical trials as a potential treatment for a variety of cancers. TL-32711 inhibits members of the inhibitor of apoptosis protein (IAP) family proteins, inducing degradation of cIAP1 and cIAP2. TL-32711 exhibits anticancer chemotherapeutic activity, inhibiting...
| Schlagworte: | Birinapant |
| Anwendung: | Antineoplastic, Smac mimetic |
| CAS | 1260251-31-7 |
| MW: | 806.94 D |
ab 94,00 €
Birinapant
Artikelnummer: TGM-T6007-100mg
Description: Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity. Target: Apoptosis, HIV Protease, IAP. Smiles:...
| Schlagworte: | TL32711 |
| Anwendung: | Antineoplastic |
| CAS | 1260251-31-7 |
| MW: | 806.94 D |
ab 39,00 €
