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Mitapivat
Artikelnummer: Cay43908-10
Mitapivat is an allosteric activator of erythrocyte pyruvate kinase (PKR). It increases PKR activity and ATP levels in red blood cells isolated from patients with pyruvate kinase deficiency when used at a concentration of 10 µM. Mitapivat increases hematocrit and hemoglobin levels, decreases osmotic fragility, and...
| Schlagworte: | AG-348 |
| Anwendung: | Allosteric pyruvate kinase PKLR activator |
| CAS | 1260075-17-9 |
| MW: | 450.56 D |
ab 116,00 €
Mitapivat
Artikelnummer: TGM-T4223-100mg
Description: Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency. Target: PKM. Smiles: O=C(N1CCN(CC2CC2)CC1)c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1. References: C Kung. Activators of pyruvate kinase M2 and methods of...
| Schlagworte: | PKR-IN-1 |
| CAS | 1260075-17-9 |
| MW: | 450.55 D |
ab 33,00 €
