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Nanatinostat
Artikelnummer: Cay43931-1
Nanatinostat is an inhibitor of histone deacetylases (HDACs). It selectively inhibits HDAC1, HDAC2, and HDAC3 over HDAC5 and HDAC6 (IC50s = 3, 4, 7, 200, and 2,100 nM, respectively). Nanatinostat inhibits proliferation in a panel of 15 cancer cell lines (GI50s = 31-750 nM). It induces cell cycle arrest at the sub-G1...
| Schlagworte: | CHR-3996,... |
| Anwendung: | HDAC inhibitor |
| CAS | 1256448-47-1 |
| MW: | 394.41 D |
ab 147,00 €
Nanatinostat
Artikelnummer: TGM-T16270-100mg
Description: Nanatinostat is an effective and class I selective inhibitor of histone deacetylase (IC50: 8 nM). Target: Others. Smiles: [H][C@@]12CN(C[C@]1([H])[C@H]2NCc1ccc2cc(F)ccc2n1)c1ncc(cn1)C(=O)NO. References: Moffat D, et al. Discovery of...
| Schlagworte: | CHR-3996 |
| Anwendung: | Targets histone deacetylase 1/2 [EC:3.5.1.98] (HDAC1_2) |
| CAS | 1256448-47-1 |
| MW: | 394.4 D |
ab 310,00 €
