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USP7/USP47 inhibitor
USP7/USP47 inhibitor

Artikelnummer: TGM-T4338-100mg

Description: USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 µM and 1.0 µM, respectively. Target: DUB. Smiles: CS(=O)(=O)c1ccc(NC(=O)c2cc(C#N)c(Sc3c(Cl)cncc3Cl)s2)cc1. References: Weinstock J, et al. Selective Dual Inhibitors of...
Schlagworte: USP7/47 inhibitor-1
Anwendung: USP7/USP47 inhibitor
CAS 1247825-37-1
MW: 484.4 D
ab 37,00 €
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USP7-USP47 Inhibitor
USP7-USP47 Inhibitor

Artikelnummer: Cay25622-1

USP7-USP47 inhibitor is a dual inhibitor of ubiquitin-specific protease 7 (USP7) and USP47 (IC50s = 0.42 and 1 µM, respectively). It is selective for USP7 and USP47 over USP2, USP5, USP8, USP21, USP28, caspase-3, and cathepsin B (IC50s = >31.6 µM). USP7-USP47 inhibitor inhibits the growth of HCT116 cells (EC50 = 7.6...
Schlagworte: 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide
Anwendung: USP7 inhibitor, USP47 inhibitor
CAS 1247825-37-1
MW: 484.4 D
ab 94,00 €
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