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P22077
Artikelnummer: Cay23704-5
P22077 is a dual inhibitor of the deubiquitylating enzymes ubiquitin-specific protease 7 (USP7) and USP47 (EC50s = 8.01 and 8.74 µM, respectively, in a fluorescence-based enzyme assay). It is selective for USP7 and USP47 over other USPs and proteases with EC50 values greater than 50 µM. P22077 (25 µM) induces the...
| Schlagworte: | 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
| Anwendung: | USP7 / USP47 inhibitor |
| CAS | 1247819-59-5 |
| MW: | 315.3 D |
ab 69,00 €
P 22077
Artikelnummer: TGM-T2424-100mg
Description: P 22077 (P22077) is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 µM. It also inhibits the closely related USP47. Target: DUB. Smiles: CC(=O)c1cc(c(Sc2ccc(F)cc2F)s1)[N+]([O-])=O. References: Tian X, et al. Assay Drug Dev Technol, 2011, 9(2), 165-173.
| Schlagworte: | P22077 |
| CAS | 1247819-59-5 |
| MW: | 315.32 D |
ab 31,00 €
