Zu "1246529-32-7" wurden 3 Artikel gefunden!
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MPI-0479605
Artikelnummer: Cay44704-1
MPI-0479605 is an inhibitor of monopolar spindle 1 (Mps1. IC50 = 1. nM). It is selective for Mps1 over a panel of 79 kinases at 500 nM. MPI-0479605 induces time-dependent degradation of cyclin B and securin and decreases phosphorylation of mitotic arrest deficient 3 (Mad3), resulting in failed cytokinesis in HeLa...
| Schlagworte: | N6-cyclohexyl-N2-[2-methyl-4-(4-morpholinyl)phenyl]-9H-purine-2,6-diamine |
| Anwendung: | Mps1 (multipolar spindle 1) inhibitor |
| CAS | 1246529-32-7 |
| MW: | 407.52 D |
ab 34,00 €
MPI-0479605
Artikelnummer: SYN-1187-M001
Soluble in DMSO. MPI-0479605 inhibits TTK kinase activity in vitro with an IC(50) of 4nM.
| Schlagworte: | MPI0479605 |
| Anwendung: | TTK inhibitor |
| CAS | 1246529-32-7 |
| MW: | 444,0 D |
ab 293,00 €
MPI-0479605
Artikelnummer: TGM-T2313-100mg
Description: MPI-0479605 is an ATP competitive and selective inhibitor. Target: Apoptosis, Kinesin. Smiles: Cl.Cc1cc(ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1)N1CCOCC1. References: Tardif KD, et al. Mol Cancer Ther. 2011, 10(12), 2267-2275.
| CAS | 1246529-32-7 |
| MW: | 407.51 D |
ab 51,00 €
