Zu "1245537-68-1" wurden 4 Artikel gefunden!
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NVP-BGT226
Artikelnummer: LKT-N8604.1
NVP-BGT225 is an inhibitor of PI3K and mTORC1/2.
| Schlagworte: | BGT226 |
| Anwendung: | PI3K / mTOR inhibitor |
| CAS | 1245537-68-1 |
| MW: | 650.6 D |
ab 215,00 €
NVP-BGT226
Artikelnummer: Cay22142-1
NVP-BGT226 is an orally bioavailable dual inhibitor of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR). It inhibits class I PI3Ks with EC50 values of 4, 63, and 38 nM for PI3Kalpha, beta, and gamma isoforms, respectively, in a filter binding assay. It binds to both class I and class...
| Schlagworte: | 1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-2H-imidazo[4,5-c]quinolin-2... |
| Anwendung: | Dual PI3K / FRAP inhibitor |
| CAS | 1245537-68-1 |
| MW: | 650.6 D |
ab 60,00 €
BGT-226 maleate
Artikelnummer: SYN-1178-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin with an IC(50) of 1nM. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Schlagworte: | NVP-BEZ226, BEZ-226 |
| Anwendung: | PI3K / mTOR inhibitor |
| CAS | 1245537-68-1 |
| MW: | 650,6 D |
ab 139,00 €
BGT226 maleate
Artikelnummer: TGM-T6072-100mg
Description: BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kalpha/beta/gamma (IC50: 4/63/38 nM) . Target: Apoptosis, Autophagy, mTOR, PI3K. Smiles: OC(=O)\C=C/C(O)=O.COc1ccc(cn1)-c1ccc2ncc3n(C)c(=O)n(-c4ccc(N5CCNCC5)c(c4)C(F)(F)F)c3c2c1. References: Chang KY, et al. Clin Cancer Res, 2011,...
| Schlagworte: | BGT226 , NVP-BGT226 (maleate) , NVP-BGT226 |
| Anwendung: | Dual PI3K / FRAP inhibitor |
| CAS | 1245537-68-1 |
| MW: | 650.6 D |
ab 31,00 €
