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TUG-469
Artikelnummer: Cay44272-10
TUG-469 is an agonist of free fatty aid receptor 1 (FFAR1/GPR40). It induces calcium mobilization in a reporter assay using cells expressing human FFAR1/GPR40 (EC50 = 18. nM). TUG-469 (10 µM) induces insulin secretion in INS-1E insulinoma cells. It inhibits increases in blood glucose levels in a glucose tolerance...
| Schlagworte: | 4-[[(2'-methyl[1,1'-biphenyl]-3-yl)methyl]amino]-benzenepropanoic acid |
| Anwendung: | FFAR1/GPR40 agonist |
| CAS | 1236109-67-3 |
| MW: | 345.44 D |
ab 40,00 €
NEU
TUG-469
Artikelnummer: TGM-T34967-25mg
Description: TUG-469 is an agonist of free fatty acid 1(FFA) receptor. Target: GPR. Smiles: Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1. References: Panse M, et al. Activation of extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) by free fatty acid receptor 1 (FFAR1/GPR40) protects from palmitate-induced...
| Schlagworte: | TUG469, TUG 469 |
| CAS | 1236109-67-3 |
| MW: | 345.43 D |
ab 45,00 €
