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Derazantinib
Artikelnummer: Cay27636-1
Derazantinib is a multi-kinase inhibitor. It is a pan inhibitor of FGF receptors (FGFRs, IC50s = 4.5, 1.8, 4.5, and 34 nM for FGFR1, -2, -3, and -4, respectively) and also inhibits 10 receptor tyrosine kinases, 8 non-receptor tyrosine kinases, and the calcium/calmodulin-dependent protein kinase QIK in a panel of 297...
| Schlagworte: | ARQ 087, (6R)-6-(2-fluorophenyl)-5,6-dihydro-N-[3-[2-[(2-methoxyethyl)amino]ethyl]phenyl]-benzo[h]quinazolin-2-amine |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 1234356-69-4 |
| MW: | 468.6 D |
ab 91,00 €
Derazantinib
Artikelnummer: TGM-TQ0228-100mg
Description: Derazantinib (ARQ-087) is a potent, ATP-competitive, orally active tyrosine kinase inhibitor with IC50 values of 4.5/1.8/4.35/3.4 nM for chondrocyte FGFR1/FGFR2/FGFR3/FGFR4, respectively. Target: FGFR. Smiles: COCCNCCc1cccc(Nc2ncc3C[C@@H](c4ccccc4F)c4ccccc4-c3n2)c1. References: Balek L, et al. ARQ 087...
| Schlagworte: | ARQ-087 |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 1234356-69-4 |
| MW: | 468.57 D |
ab 46,00 €
