Zu "1234015-52-1" wurden 3 Artikel gefunden!
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LY2606368
Artikelnummer: Cay21490-1
LY2606368 is a checkpoint kinase 1 (Chk1) inhibitor with a Ki value of 0.9 nM against the purified target and IC50 values of In vitro, LY2606368 inhibits the doxorubicin-activated G2/M checkpoint in p53-deficient HeLa cells with an EC50 value of 9 nM. LY2606368, at 25 nM, also significantly induces apoptosis and...
| Schlagworte: | Prexasertib, 5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]-2-pyrazinecarbonitrile |
| Anwendung: | CHK1 inhibitor |
| CAS | 1234015-52-1 |
| MW: | 365.4 D |
ab 45,00 €
LY-2606368
Artikelnummer: LKT-L960006.100
CHK1 inhibitor.
| Schlagworte: | LY 2606368, LY2606368, Prexasertib |
| Anwendung: | CHK1 inhibitor |
| CAS | 1234015-52-1 |
| MW: | 365.4 D |
ab 188,00 €
Prexasertib
Artikelnummer: TGM-T4310-100mg
Description: Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). Prexasertib causes double-stranded DNA breaks and replication mutations, leading to apoptosis. Prexasertib has antitumor activity. Target: Apoptosis, Chk. Smiles:...
| Schlagworte: | LY2606368 |
| Anwendung: | Targets serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] (CHEK1) |
| CAS | 1234015-52-1 |
| MW: | 365.39 D |
ab 44,00 €
