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HA-130
HA-130

Artikelnummer: Cay10498-5

HA-130 is a reversible inhibitor of autotaxin, completely blocking the hydrolysis of the substrate bis-pNPP with an IC50 value of 28 nM. It does not affect the activity of any proteasomal protease or related enzymes. HA-130 rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1...
Schlagworte: B-[3-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid
Anwendung: Reversible autotaxin inhibitor
CAS 1229652-21-4
MW: 463.3 D
ab 108,00 €
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HA130
HA130

Artikelnummer: TGM-T2646-100mg

Description: HA130 is a selective ATX (autotaxin) inhibitor. Target: PDE. Smiles: OB(O)c1cccc(COc2ccc(\C=C3/SC(=O)N(Cc4ccc(F)cc4)C3=O)cc2)c1. References: Zhang Y, et al. J Immunol. 2012 Oct 15,189(8):3914-3924.
CAS 1229652-21-4
MW: 463.29 D
ab 32,00 €
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