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XE 991 (hydrochloride)
XE 991 (hydrochloride)

Artikelnummer: Cay14582-10

The KCNQ potassium channels are neuronal modulators which combine with other KQT or KCNE channels to form heteromultimers. XE 991 is a blocker of KCNQ channels that potently inhibits KCNQ1 and 2 homomeric channels (IC50 = 0.75 and 0.71 µM, respectively) as well as KCNQ2+3 heteromultimers (IC50 = 0.6 µM). It much...
Schlagworte: 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone, dihydrochloride
Anwendung: KCNQ channel blocker
CAS 122955-13-9
MW: 449.4 D
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