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Mps1-IN-2
Artikelnummer: TGM-T1839-1mg
Description: Mps1-IN-2 is a potent, selective, and ATP-competitive inhibitor of both Mps1 and Plk1. Target: Kinesin, PLK. Smiles: CCOc1cc(ccc1Nc1ncc2N(C)C(=O)CCN(C3CCCC3)c2n1)N1CCC(O)CC1. References: Kwiatkowski N, et al. Nat Chem Biol. 2010 May,6(5):359-68.
| Anwendung: | MPS1 inhibitor |
| CAS | 1228817-38-6 |
| MW: | 480.6 D |
34,00 €
Mps1-IN-2
Artikelnummer: Cay19401-1
Mps1-IN-2 is an ATP-competitive inhibitor of the checkpoint kinase Mps1 (IC50 = 145 nM). It is 1,000-fold selective for Mps1 over a panel of 352 kinases at 10 µM, but does inhibit Plk1 (Kd = 61 nM).Formal Name:...
| Schlagworte: | 9-cyclopentyl-2-[[2-ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,7,8,9-tetrahydro-5-methyl-6H-pyrimido[4,5-b][1,4]dia... |
| Anwendung: | MPS1 inhibitor |
| CAS | 1228817-38-6 |
| MW: | 480.6 D |
ab 44,00 €
