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Vesatolimod
Artikelnummer: TGM-T6846-100mg
Description: Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7. Target: TLR, HBV, HCV Protease, HIV Protease, Apoptosis. Smiles: CCCCOc1nc(N)c2NC(=O)CN(Cc3cccc(CN4CCCC4)c3)c2n1. References: Rebbapragada I, et al. Molecular Determinants of GS-9620-Dependent TLR7...
| Schlagworte: | GS-9620 |
| Anwendung: | Targets toll-like receptor 7 (TLR7) |
| CAS | 1228585-88-3 |
| MW: | 410.51 D |
ab 45,00 €
GS-9620
Artikelnummer: Cay19628-25
GS-9620 is an orally available agonist of toll-like receptor 7 (TLR7, EC50 = 291 nM) with 30-fold selectivity over TLR8 (EC50 = 9 µM). It has been shown to stimulate a TLR7 immune response in two different animal models of chronic hepatitis B infection and to inhibit HIV-1 infection in human peripheral blood...
| Schlagworte: | Vesatolimod, 4-amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-6(5H)-pteridinone |
| Anwendung: | TLR7 agonist |
| CAS | 1228585-88-3 |
| MW: | 410.5 D |
ab 85,00 €
