Zu "1227911-45-6" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
GSK2334470
Artikelnummer: Cay18095-5
3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that plays an important role in growth factor signaling by phosphorylating and activating a group of kinases, including protein kinase (PK)B, PKA, and certain isoforms of PKC. GSK2334470 is an inhibitor of PDK1 (IC50 = ~10 nM) that...
| Schlagworte: | (3S,6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide |
| Anwendung: | PDPK1 inhibitor |
| CAS | 1227911-45-6 |
| MW: | 462.6 D |
ab 118,00 €
GSK2334470
Artikelnummer: LKT-G7344.5
GSK2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).
| Schlagworte: | GSK-2334470,... |
| Anwendung: | PDPK1 inhibitor |
| CAS | 1227911-45-6 |
| MW: | 462.59 D |
ab 94,00 €
GSK2334470
Artikelnummer: TGM-T2348-10mg
Description: GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases. Target: PDK. Smiles: CNc1nc(cc(n1)-c1ccc2c(N)n[nH]c2c1)N1C[C@H](CC[C@H]1C)C(=O)NC1CCCCC1. References: Najafov A, et al. Biochem J, 2011, 433(2), 357-369.
| CAS | 1227911-45-6 |
| MW: | 462.59 D |
ab 46,00 €
