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NEU
GNF351
Artikelnummer: BPS-84091-1
GNF351 is a potent AhR (aryl hydrocarbon receptor) antagonist. Aryl hydrocarbon receptor (AhR) is a ligand-dependent nuclear receptor that functions as a transcription factor. It can follow a canonical signaling pathway where binding of ligands to the cytosolic AhR induces the formation of a complex that...
| Schlagworte: | AHR, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76 |
| Anwendung: | Cellular assays |
| CAS | 1227634-69-6 |
| MW: | 411.50 D |
ab 367,00 €
GNF351
Artikelnummer: TGM-T15410-100mg
Description: GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM). Target: Aryl...
| CAS | 1227634-69-6 |
| MW: | 411.5 D |
ab 36,00 €
