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(±)-Ibutilide (hemifumarate)
(±)-Ibutilide (hemifumarate)

Artikelnummer: Cay15011-100

(±)-Ibutilide is a class III antiarrhythmic agent. It inhibits the rapidly activating delayed-rectifier potassium current (IKr) in AT-1 myocytes with an IC50 value of 20 nM. (±)-Ibutilide also enhances the late inward sodium current (INa) and increases the action potential duration in isolated guinea pig ventricular...
Schlagworte: U-70226E, N-[4-[4-(ethylheptylamino)-1-hydroxybutyl]phenyl]-methanesulfonamide, 2E-butenedioate (2:1)
Anwendung: Potassium channel blocker
CAS 122647-32-9
MW: 442.6 D
ab 127,00 €
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Ibutilide Fumarate
Ibutilide Fumarate

Artikelnummer: TGM-T6541-100mg

Description: Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action...
Schlagworte: Corvert Fumarate, U70226E
Anwendung: Targets potassium voltage-gated channel Eag-related subfamily H member 2 (KCNH2, KV11.1)
CAS 122647-32-9
MW: 885.23 D
ab 48,00 €
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