Zu "1225037-39-7" wurden 2 Artikel gefunden!
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Bimiralisib
Artikelnummer: Cay23441-1
Bimiralisib is a potent and orally bioavailable inhibitor of phosphatidylinositol 3-kinases (PI3Ks, IC50s = 33, 661, 708, and 451 nM for PI3Kalpha, PI3Kbeta, PI3Kgamma, and PI3Kdelta, respectively) and the mammalian target of rapamycin (mTOR, IC50 = 89 nM). It is selective for these kinases over a panel of cell...
| Schlagworte: | PI3K-IN-2, 5-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)-2-pyridinamine |
| Anwendung: | PI3K inhibitor |
| CAS | 1225037-39-7 |
| MW: | 411.4 D |
ab 57,00 €
Bimiralisib
Artikelnummer: TGM-T2265-100mg
Description: Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth...
| Schlagworte: | 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine , PQR309 , PI3K-IN-2 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 1225037-39-7 |
| MW: | 411.38 D |
ab 30,00 €
