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D-Lin-MC3-DMA
D-Lin-MC3-DMA

Artikelnummer: TGM-T5823-25mg

Description: D-Lin-MC3-DMA, an ionizable cationic lipid, serves as a potent siRNA delivery vehicle. Target: Others. Smiles: CCCCC\C=C/C\C=C/CCCCCCCCC(CCCCCCCC\C=C/C\C=C/CCCCC)OC(=O)CCCN(C)C. References: Kulkarni J A , Myhre J L , Chen S , et al. Design of lipid nanoparticles for, in vitro, and, in vivo, delivery of...
CAS 1224606-06-7
MW: 642.09 D
ab 34,00 €
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Lipid-based Drug Delivery-Tools
DLin-MC3-DMA
DLin-MC3-DMA

Artikelnummer: Cay34364-25

DLin-MC3-DMA is an ionizable cationic amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of Factor VII siRNA in DLin-MC3-DMA-containing LNPs reduces plasma Factor VII protein levels in mice. Formulations containing...
Schlagworte: MC3, 4-(dimethylamino)-butanoic acid, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
Anwendung: Ionizable amino lipid
CAS 1224606-06-7
MW: 642.1 D
ab 85,00 €
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