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MMP13-IN-3
MMP13-IN-3

Artikelnummer: TGM-T16124-100mg

Description: MMP13-IN-3 is >1000 selective over other MMPs. MMP13-IN-3 is an effective, selective, and orally active MMP-13 inhibitor (IC50=1 nM) for the potential treatment of osteoarthritis. Target: MMP. Smiles: CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O. References: Taylor SJ, et al....
Anwendung: MMP13 inhibitor
CAS 1222173-37-6
MW: 446.46 D
ab 84,00 €
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BI-4394
BI-4394

Artikelnummer: Cay36855-1

BI-4394 is an inhibitor of matrix metalloproteinase-13 (MMP-13, IC50 = 0.001 µM for the recombinant human enzyme). It is selective for MMP-13 over MMP-1-3, 7-10, -12, and -14 with IC50 values ranging from 8.3 to greater than 22 µM for the recombinant human enzymes. BI-4394 inhibits the degradation of isolated bovine...
Schlagworte: 5-[3-[[[(4-carboxyphenyl)methyl]amino]carbonyl]-1-methyl-1H-pyrazol-5-yl]-1H-indole-2-carboxylic acid, 2-ethyl ester
Anwendung: MMP13 inhibitor
CAS 1222173-37-6
MW: 446.5 D
ab 137,00 €
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