Zu "1221186-53-3" wurden 3 Artikel gefunden!
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TEPP-46
Artikelnummer: TGM-T7214-100mg
Description: TEPP-46 (ML265) is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1, PKL and PKR,induces tetramerization and reduces tumor formation and size in a mouse xenograft model. . Target: PKM. Smiles: Cn1c2cc(sc2c2cnn(Cc3cccc(N)c3)c(=O)c12)S(C)=O. References: Walsh M J , Brimacombe K R...
| Schlagworte: | ML265 |
| Anwendung: | PKM2 activator |
| CAS | 1221186-53-3 |
| MW: | 372.46 D |
ab 42,00 €
ML-265
Artikelnummer: Cay13942-10
Pyruvate kinase catalyzes the final step in glycolysis, the formation of pyruvate and ATP from phosphoenolpyruvate and ADP. The expression of the M2 isozyme of pyruvate kinase (PKM2) plays an important role in the metabolic reprogramming of tumor cells, which require high amounts of glucose for proliferation. PKM2...
| Schlagworte: | CID-44246499, NCGC00186528, TEPP-46,... |
| Anwendung: | PKM2 activator |
| CAS | 1221186-53-3 |
| MW: | 372.5 D |
ab 36,00 €
ML-265
Artikelnummer: AG-CR1-3687-M001
Potent and selective cell permeable pyruvate kinase M2 (PKM2) activator with little or no activity versus PKM1, PKL and PKR. Useful agent for immunometabolism research. Anticancer (reducing tumor sizes in mice) and anti-inflammatory agent. Shown to bind the enzyme PKM2 to promote formation of stable,...
| Schlagworte: | TEPP-46, ML265, NCGC00186528, CID-44246499 |
| Anwendung: | PKM2 activator |
| CAS | 1221186-53-3 |
| MW: | 372.5 D |
ab 39,00 €
