Zu "1218942-37-0" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
GKT137831
Artikelnummer: Cay17764-1
NADPH oxidase 1 (NOX1) and NOX4 generate reactive oxygen species (ROS) that are critical in regulating a variety of cellular functions but also contribute to many diseases. GKT137831 is a dual inhibitor of both NOX1 and NOX4 with Ki values in the range of 100 to 150 nM in cell-free assays of ROS production. It shows...
| Schlagworte: | 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione |
| Anwendung: | NOX1 & NOX4 inhibitor |
| CAS | 1218942-37-0 |
| MW: | 394.9 D |
ab 49,00 €
Setanaxib
Artikelnummer: TGM-T6099-2mg
Description: Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor. Target: Ferroptosis, NADPH-oxidase, NADPH. Smiles: CN(C)c1cccc(c1)-c1n(C)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12. References: Aoyama T, et al. Hepatology. 2012, 56(6), 2316-2327.
| Schlagworte: | GKT137831 |
| Anwendung: | NOX1 & NOX4 inhibitor |
| CAS | 1218942-37-0 |
| MW: | 394.85 D |
ab 33,00 €
